Duloxetine hcl msds

buy now

Get the complete Material Safety Data Sheet (MSDS) for duloxetine hydrochloride (HCl) to ensure the safe handling and usage of this medication. This comprehensive document outlines critical information on the properties, hazards, and precautions associated with duloxetine HCl. Protect yourself and others with accurate MSDS information – a must-have for professionals in the pharmaceutical industry.

Safety Data Sheet

The Safety Data Sheet (SDS) for duloxetine hcl provides detailed information on the chemical properties, hazards, handling procedures, and emergency response measures for this substance. It is essential to refer to the SDS before using or handling duloxetine hcl to ensure safety and compliance with regulatory requirements.

Key Information in the Safety Data Sheet:

  • Chemical Name: Duloxetine HCl
  • Chemical Formula: C18H19NOS•HCl
  • Molecular Weight: 333.87 g/mol

The SDS outlines the physical and chemical properties of duloxetine hcl, including its appearance, odor, solubility, and stability. It also provides information on potential hazards, such as flammability, reactivity, and health effects, as well as safety measures to mitigate risks during handling and storage.

Handling and Storage Recommendations:

Handling and Storage Recommendations:

  • Store duloxetine hcl in a cool, dry, well-ventilated area away from incompatible materials.
  • Avoid contact with skin, eyes, and clothing. Use appropriate personal protective equipment.
  • Handle the substance in a fume hood or with adequate ventilation to prevent inhalation exposure.

Refer to the Safety Data Sheet for detailed instructions on safe handling, storage, disposal, and emergency response procedures for duloxetine hcl. Always follow the recommended precautions to ensure the health and safety of personnel and the environment.

See also  Duloxetine vs zoloft

Chemical Properties

Duloxetine hcl is a white to slightly off-white solid, which is soluble in water and ethanol. It has a molecular weight of 333.88 g/mol. The chemical formula is C18H19NOS•HCl.

Physical Properties

The melting point of duloxetine hydrochloride is approximately 255-260°C. It is stable under normal conditions of use and storage.

Duloxetine hcl has a pH of around 5.5-6.5 in a 0.1M aqueous solution. It is a weak base with a pKa of about 9.5.

Handling and Storage

It is important to handle Duloxetine HCL with care to ensure safety and efficacy. Follow these guidelines for proper handling and storage:


– Always wear appropriate personal protective equipment (PPE) such as gloves and safety glasses when handling the chemical.

– Avoid direct skin contact or inhalation of the powder. In case of contact, immediately wash the affected area with soap and water.

– Use in a well-ventilated area to prevent inhalation of vapors.


– Store Duloxetine HCL in a cool, dry place away from direct sunlight and sources of heat.

– Keep the container tightly closed when not in use to prevent contamination or moisture exposure.

– Store away from incompatible materials and follow any specific storage requirements provided in the Safety Data Sheet.

By following these handling and storage guidelines, you can ensure the safe and proper use of Duloxetine HCL.

First Aid Measures

In case of skin contact, immediately wash with plenty of soap and water. Remove contaminated clothing and wash before reuse. If skin irritation persists, seek medical advice.

If swallowed, do not induce vomiting. Seek medical attention immediately and provide the Safety Data Sheet or label to medical personnel.

See also  Duloxetine 60 mg tablets

Eye Contact

In case of contact with eyes, rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Seek medical attention if irritation persists.

Note: It is important to always read and understand the Safety Data Sheet before handling any chemical. Proper protective equipment and training should be provided to all individuals working with the chemical.

Exposure Controls

Exposure Controls

Engineering Controls: Ensure adequate ventilation to control airborne concentrations below the exposure limits. Use process enclosures, local exhaust ventilation, or other engineering controls to minimize exposure to airborne contaminants.

Personal Protective Equipment: Wear appropriate personal protective equipment, including goggles, gloves, and a respirator as needed, based on the specific exposure scenario.

Respiratory Protection: If respiratory protection is required, ensure that it is properly selected, used, and maintained in accordance with regulatory requirements. Follow a respiratory protection program that meets the requirements of OSHA Respiratory Protection Standard (29 CFR 1910.134) or equivalent.

Eye Protection: Wear chemical safety goggles or a face shield if eye contact is possible. Ensure eye protection meets the requirements of ANSI Z87.1 or equivalent.

Hand Protection: Wear chemical-resistant gloves as needed to prevent skin contact. Consult glove manufacturer for specific recommendations.

Skin Protection: Wear appropriate protective clothing to prevent skin contact. Wash contaminated clothing before reuse.

Hygiene Measures: Wash hands and face thoroughly after handling the chemical. Do not eat, drink, or smoke while working with the substance.

Disposal Considerations

Proper disposal of duloxetine hcl is essential to protect the environment and human health. Follow the guidelines below to dispose of this substance safely:

See also  Tapering off duloxetine
Method: Dispose of duloxetine hcl in accordance with local regulations and guidelines for hazardous waste disposal.
Container: Use a tightly sealed container to prevent leakage or spillage during transportation.
Disposal: Do not dispose of duloxetine hcl in household trash or sewer systems. Contact a licensed waste disposal company for proper disposal.
Recommendation: It is recommended to seek professional advice on the safe disposal of duloxetine hcl to ensure compliance with environmental regulations.